Management of cirrhosis and ascites.
نویسندگان
چکیده
From the Liver Unit, Hospital Clinic and University of Barcelona, Institut d’Investigacions Biomèdiques August Pi-Sunyer, Barcelona, Spain (P.G., A.C., V.A., J.R.); and the Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston (A.C.). Address reprint requests to Dr. Ginès at the Liver Unit, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain, or at [email protected].
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Received: 16 Oct, 2012 Accepted: 22 Dec, 2012 Background & Aims : Liver cirrhosis is associated with coagulation disorders due to decreased synthesis of clotting and inhibitor factors. It has been hypothesized that ascites plays an important role in hyperfibrinolytic state and increased risk of bleeding. We have studied the role of ascites in the hyper fibrinolytic state and relationsh...
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Cirrhosis is a major cause of morbidity and mortality worldwide with liver transplantations as it only possible cure. In the face of a significant organ shortage many patients die waiting. A major complication of cirrhosis is the development of portal hypertension and ascites. The management of ascites has barely evolved over the last hundred years and includes only a few milestones in our trea...
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Ascites refer to accumulation of fluids in the peritoneal cavity. Ascites is caused by multiple causes, among which liver cirrhosis is the commonest. Confirming the etiology is the first and most important step toward proper management. Assuming that ascites is always caused by cirrhosis can lead to unnecessarily sending patients with different etiologies for liver transplantation, particularly...
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ورودعنوان ژورنال:
- The New England journal of medicine
دوره 350 16 شماره
صفحات -
تاریخ انتشار 2004